Beacon v2

Beacon v2 is an API specification established by the Global Alliance for Genomics and Health initiative (GA4GH) that defines an open standard for federated discovery of genomic and phenotypic data in biomedical research and clinical applications.

The current version of the specification is v2 and consists of two components, the Framework and the Models. The Framework defines the format for the requests and responses, whereas the Models define the structure of the biological data response. The overall function of these two components is to provide the instructions to design a REST API (REpresentational State Transfer Application Programming Interface) with OpenAPI Specification (OAS). The OAS defines a standard, language-agnostic interface that is used by software developers to implement REST APIs.

Framework and Models


Beacon v2 and Beacon Networks: a "lingua franca" for federated data discovery in biomedical genomics, and beyond. Jordi Rambla, Michael Baudis, Tim Beck, Lauren A. Fromont, Arcadi Navarro, Manuel Rueda, Gary Saunders, Babita Singh, J.Dylan Spalding, Juha Tornroos, Claudia Vasallo, Colin D.Veal, Anthony J.Brookes. Human Mutation (2022) DOI.